Apostasy
Apostasy is a total desertion of or departure from one's religion, principles, party, cause, etc.
In his first letter to Timothy, Paul laments that his friends Alexander and Hymenaeus have succumbed to apostasy.
Among these are Hymenaeus and Alexander, whom I have handed over to Satan, so that they will be taught not to blaspheme. (I Timothy 1:20, NASB)
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